منابع مشابه
Synthetic approaches toward sesterterpenoids.
Sesterterpenoids account for many bioactive natural products, often with unusual and complex structural features, which makes them attractive targets for synthetic chemists. This review surveys efforts undertaken toward the synthesis of sesterterpenoids, focusing on completed total syntheses and covering ca. 50 natural products in total.
متن کاملSynthesis of Bioconjugate Sesterterpenoids with Phospholipids and Polyunsaturated Fatty Acids.
A series of sesterterpenoid bioconjugates with phospholipids and polyunsaturated fatty acids (PUFAs) have been synthesized for biological activity testing as antiproliferative agents in several cancer cell lines. Different substitution analogues of the original lipidic ether edelfosine (1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine) are obtained varying the sesterterpenoid in position 1...
متن کاملImidazolium Salts with Dihydroxyacetophenone Skeleton with Anticipated Anticancer Activity. II
We report herein a feasible study concerning syntheses and structure of some diazolium salts with dihydroxyacetophenone skeleton of anticipated anticancer activity. A fast, general and facile method for preparation of 1,3-diazol salts via N-alkylation reactions under conventional heating and microwave irradiation is presented. The microwaves remarkably accelerated these N-alkylations, the react...
متن کاملCytotoxic Sesterterpenoids from a Sponge Hippospongia sp.
One new pentacyclic sesterterpene, hippospongide A (1), and one new scalarane sesterterpenoid, hippospongide B (2), along with six previously reported known scalarane-type sesterterpenes (3-8), were isolated from a sponge Hippospongia sp. The structures of these compounds were elucidated on the basis of their spectroscopic data and comparison of the NMR data with those of known analogues. These...
متن کاملAnticancer Activity of Amauroderma rude
More and more medicinal mushrooms have been widely used as a miraculous herb for health promotion, especially by cancer patients. Here we report screening thirteen mushrooms for anti-cancer cell activities in eleven different cell lines. Of the herbal products tested, we found that the extract of Amauroderma rude exerted the highest activity in killing most of these cancer cell lines. Amauroder...
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ژورنال
عنوان ژورنال: Current Medicinal Chemistry
سال: 2015
ISSN: 0929-8673
DOI: 10.2174/0929867322666150821101047